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| REGION | GAME | VENUE | TIME | TV | ANNOUNCERS |
|---|---|---|---|---|---|
| South | Stanford Cardinal (10) vs. Kansas Jayhawks (2) | Scottrade Center (St. Louis, MO) | 1215p | CBS | Jim Nantz/Greg Anthony/Tracy Wolfson |
| MidWest | Kentucky Wildcats (8) vs. Wichita State Shockers (1) | Scottrade Center (St. Louis, MO) | 245p | CBS | Jim Nantz/Greg Anthony/Tracy Wolfson |
| East | North Carolina Tar Heels (6) vs. Iowa State Cyclones (3) | AT&T Center (San Antonio, TX) | 515p | CBS | Marv Albert/Steve Kerr/Craigh Sager |
| MidWest | Mercer Bears (14) vs. Tennessee Volunteers (11) | PNC Arena (Raleigh, NC) | 610p | TNT | Kevin Harlan/Len Elmore/Reggie Miller/Rachel Nichols |
| South | Stephen F. Austin Lumberjacks (12) vs. UCLA Bruins (4) | Viejas Arena at Aztec Bowl (San Diego, CA) | 710p | TBS | Andrew Catalon/Mike Gminski/Otis Livingston |
| West | Baylor Bears (6) vs. Creighton Bluejays (3) | AT&T Center (San Antonio, TX) | 745p | truTV | Marv Albert/Steve Kerr/Craigh Sager |
| East | Memphis Tigers (8) vs. Virginia Cavaliers (1) | PNC Arena (Raleigh, NC) | 840p | TNT | Kevin Harlan/Len Elmore/Reggie Miller/Rachel Nichols |
| West | Gonzaga Bulldogs (8) vs. Arizona Wildcats (1) | Viejas Arena at Aztec Bowl (San Diego, CA) | 940p | TBS | Andrew Catalon/Mike Gminski/Otis Livingston |