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The Round of 32 will tip off on Saturday with three #1 seeds playing as the Second Round games are played in Providence, Des Moines, Raleigh, and Denver.
Winners of these games will book a spot in the Sweet 16.
Saturday, March 19: 2nd Round Games
| Time | TV | Location | Region | Game | PLAY-BY-PLAY/ANALYST//REPORTER |
|---|---|---|---|---|---|
| 12:10p |  |
Providence | South | (3) Miami-Florida Hurricanes vs. (11) Wichita State Shockers | Ian Eagle/Chris Webber/Len Elmore//Evan Washburn |
| After Conc. | |
Providence | West | (4) Duke Blue Devils vs. (12) Yale Bulldogs | Eagle/Webber/Elmore//Washburn |
| 5:15p | |
Des Moines | East | (4) Kentucky Wildcats vs. (5) Indiana Hoosiers | Jim Nantz/Grant Hill/Bill Raftery//Tracy Wolfson |
| 6:10p |  |
Denver | Midwest | (4) Iowa State Cyclones vs. (12) Arkansas-Little Rock Trojans | Andrew Catalon/Steve Lappas//Jamie Erdahl |
| 7:10p |  |
Raleigh | Midwest | (1) Virginia Cavaliers vs. (9) Butler Bulldogs | Kevin Harlan/Reggie Miller/Dan Bonner//Lewis Johnson |
| After Conc. | |
Des Moines | South | (1) Kansas Jayhawks vs. (9) Connecticut Huskies | Nantz/ Hill/ Raftery//Wolfson |
| After Conc. | |
Denver | Midwest | (3) Utah Utes vs. (11) Gonzaga Bulldogs | Catalon/Lappas//Erdahl |
| After Conc. | |
Raleigh | East | (1) North Carolina Tar Heels vs. (9) Providence Friars | Harlan/Miller/Bonner//Johnson |